Marburg virus

One confirmed case, nine deaths and 16 suspected cases have been reported from two communities in this province. This is the first MVD outbreak that has ever ...

The Africa CDC has deployed a team of experts in Equatorial Guinea to support response efforts in the country. The African Union spearheads Africa’s development and integration in close collaboration with African Union Member States, the Regional Economic Communities and African citizens. With partners’ support, the Ministry of Health and Social welfare has deployed rapid response teams to support further investigations. MVD is a severe and often fatal illness in humans, and is a zoonotic hemorrhagic disease caused by the Marburg virus. The source of this outbreak is still unclear and genome sequencing results are still pending. The initial confirmed case and other suspected cases presented with fever, fatigue, bloodstained vomit and diarrhoea.

The World Health Organization convened an urgent meeting to evaluate vaccine candidates after nine deaths and 16 suspected cases were reported.

The organization said it will work with clinicians and health officials in Equatorial Guinea to determine what a trial might look like. Attendees at the WHO meeting discussed five vaccine candidates that have shown promise against Marburg virus in animal studies. [according to the Centers for Disease Control and Prevention](https://www.cdc.gov/vhf/marburg/symptoms/index.html). Before this, the most recent Marburg outbreak was in Ghana in July. George Ameh, the WHO’s representative in Equatorial Guinea, said the organization has ramped up contact tracing. On Tuesday, the WHO convened an urgent meeting to evaluate several possible vaccine candidates that could be administered during the outbreak.

Cameroonian authorities detect two suspected cases of Marburg disease on the border with Equatorial Guinea, where nine people have died.

"On the 13th of February, we had two suspected cases. The disease is suspected to have now crossed the border with two cases detected in Olamze, according to the public health delegate for the region. Cameroonian authorities have detected two suspected cases of Marburg disease on the border with Equatorial Guinea, where an outbreak has killed at least nine people.

An outbreak of an incurable, killer disease has left health authorities around the world on edge after nine...

"Thanks to the rapid and decisive action by the Equatorial Guinean authorities in confirming the disease, emergency response can get to full steam quickly so that we save lives and halt the virus as soon as possible." So far, all known cases have been detected in the Kie-Ntem province, where authorities are now desperately working to stop the spread and treat infected before the virus leaks further across the continent. [killer disease](http://9news.com.au/virus)has left [health](http://9news.com.au/health)authorities on edge after nine people died suddenly in [Equatorial Guinea in Africa](http://9news.com.au/africa).

Equatorial Guinea has reported nine deaths and sixteen suspected cases of Marbug virus disease, and Cameroon has reported an additional two suspected cases, ...

[few hundred readily available doses](https://www.statnews.com/2023/02/14/marburg-outbreak-race-to-test-vaccines-drugs/), according the Helen Braswell, reporting on an [emergency meeting of the World Health Organization](https://www.who.int/news-room/events/detail/2023/02/14/default-calendar/who-urgent-marburg-meeting). [basic reproduction number (R0) was measured to be around 1.6](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050948) for the 2005 outbreak in Angola, similar to that of seasonal influenza. Peak infectiousness is estimated to be reached around [10 days since infection](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050948). Although the area of Cameroon where the two suspected cases were identified is adjacent to the presumptive origin in Equatorial Guinea, it is worrying that [neither case had a travel history](https://www.reuters.com/world/africa/who-increasing-health-surveillance-after-equatorial-guinea-finds-marburg-virus-2023-02-14/), suggesting that unobserved local transmission may be ongoing in both countries. In only four of these outbreaks did the number of cases reach double digits, but two were quite large (154 cases in the Democratic Republic of the Congo in 1998-2000 and 252 cases in Angola in 2004-2005), showing that sustained transmission is possible. It is probable that additional cases will be discovered. The present one creates the possibility of testing those vaccines in the field, but deployment would need to be immediate and with such a small outbreak it is hard to guess what distribution would be optimal. I’m a scientist. Past spillover events have occurred in Angola, the Democratic Republic of Congo, Ghana, Guinea, Kenya, Uganda, and Zimbabwe, showing that Marburg is not geographically isolated. Unfortunately, supplies are limited to only a This means that the raw case fatality rate is about 80%. Outbreaks are believed to start with the spillover of the virus from fruit bats into human population.

Equatorial Guinea has confirmed its first outbreak of the Marburg virus, a highly infectious and deadly disease similar to Ebola, following the deaths of at ...

A WHO emergency response has been activated after reports of nine deaths and 16 more suspected cases of Marburg virus in Equatorial Guinea.

“On the 13 of February, we had two suspected cases. These are two 16-year-old children, a boy and a girl, who have no previous travel history to the affected areas in Equatorial Guinea,” Bidjang said at a meeting in Cameroon’s capital Yaounde. There are no approved vaccines or antiviral treatments to treat it.

The World Health Organisation convened for an “urgent” meeting on Tuesday in response to an outbreak of the deadly Marburg virus in Africa.

Seven people who were exposed to the virus while conducting research on monkeys died. redeployed the Covid-19 teams that were there for contact tracing and quickly retrofitted them to really help us out,” Dr Ameh said. “Contact tracing, as you know, is a cornerstone of the response. Last year, there were two reported Marburg deaths in Ghana. It causes haemorrhagic fever with a fatality ratio as high as 88% — far deadlier than its better-known cousin the Ebola virus, which has wreaked havoc across parts of Africa. The World Health Organisation convened for an “urgent” meeting on Tuesday in response to an outbreak of the deadly Marburg virus in Africa.

WHO announced that Equatorial Guinea confirmed its first outbreak of the rare disease.

[the African fruit batopens in a new tab or window](https://www.cdc.gov/vhf/marburg/transmission/index.html), a sighted cave-dwelling bat found across Africa. Around day 5 of symptoms, a maculopapular rash, most prominent on the trunk, may occur. Other symptoms may include nausea, vomiting, chest pain, sore throat, abdominal pain, and diarrhea. [fatality rateopens in a new tab or window](https://www.cdc.gov/vhf/marburg/symptoms/index.html) is 23% to 90%. [Marburg virus vaccine consortiumopens in a new tab or window](https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010805) (MARVAC). [incubation periodopens in a new tab or window](https://www.cdc.gov/vhf/marburg/symptoms/index.html) for Marburg virus disease is 2 to 21 days. In addition, 15 cases occurred in Uganda in 2012. [Supportive therapyopens in a new tab or window](https://www.cdc.gov/vhf/marburg/treatment/index.html) should be used in the hospital, including balancing the patient's fluids and electrolytes, maintaining oxygen status and blood pressure, replacing lost blood and clotting factors, and treatment for any complicating infections. [according to the CDCopens in a new tab or window](https://www.cdc.gov/vhf/marburg/outbreaks/chronology.html). Fruit bats do not show signs of infection. [sub-Saharan Africaopens in a new tab or window](https://www.cdc.gov/vhf/marburg/outbreaks/distribution-map.html), and the rare case in travelers, mostly returning from African countries. [antiviral treatmentopens in a new tab or window](https://www.cdc.gov/vhf/marburg/treatment/index.html) for this hemorrhagic fever, which can cause severe illness and death.

Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, the public ...

“On the 13th of February, we had two suspected cases. There are no vaccines or antiviral treatments approved to treat it. Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, the public health delegate for the region, Robert Mathurin Bidjang, said on Tuesday.

Control measures such as quarantine could end the outbreak in Equatorial Guinea quickly — good news for inhabitants but a mixed blessing for clinical ...

It’s good news for public health and the people of Equatorial Guinea, but perhaps bad news for science.” None of the vaccines is available in large quantities, developers said at the meeting: availability ranges from a few hundred doses in the case of the Sabin and PHV vaccines to a few thousand for Janssen’s candidate. At this week’s WHO meeting, officials discussed the practicalities of testing Marburg virus vaccines in Equatorial Guinea.

News and Press Release in English on Equatorial Guinea about Health and Epidemic; published on 14 Feb 2023 by Africa CDC.

The Africa CDC has deployed a team of experts in Equatorial Guinea to support response efforts in the country. The African Union spearheads Africa’s development and integration in close collaboration with African Union Member States, the Regional Economic Communities and African citizens. With partners’ support, the Ministry of Health and Social welfare has deployed rapid response teams to support further investigations. AU Vision: to accelerate progress towards an integrated, prosperous and inclusive Africa, at peace with itself, playing a dynamic role in the continental and global arena, effectively driven by an accountable, efficient and responsive Commission. MVD is a severe and often fatal illness in humans, and is a zoonotic hemorrhagic disease caused by the Marburg virus. One confirmed case, nine deaths and 16 suspected cases have been reported from two communities in this province.

The deadly Marburg virus has been detected in Equatorial Guinea and neighbouring Cameroon, and the World Health Organization is deploying teams to trace the ...

The WHO and Equatorial Guinea officials are also in discussions about potentially testing experimental therapeutics in the region. [50 per cent](https://www.who.int/news-room/fact-sheets/detail/marburg-virus-disease) of people with Marburg virus die from the disease, though fatality rates can range from 24 to 88 per cent depending on the virus strain. “Any decision on trials of [Marburg virus] vaccines and therapeutics will be made by national authorities and researchers in Equatorial Guinea,” said Ghebreyesus. It is also assisting officials in Cameroon and Gabon to prepare for rapidly detecting, isolating and providing care to people who may contract Marburg virus. Officials suspect at least eight other people in Equatorial Guinea have died from the virus. This comes days after an outbreak was confirmed in neighbouring Equatorial Guinea – the country’s first such outbreak – after a recently deceased person tested positive for the disease.