Cystic fibrosis

Levels of specific fat-like lipids in saliva were found to be closely linked to cystic fibrosis (CF) complications like poor lung function.

These data need to be confirmed in larger populations of participants investigating the impact of diet and treatment on CF lipid profiles, they noted. Altogether, concentrations of 12 lipids were commonly altered in the saliva of CF patients across all comparisons. Aeruginosa infection included two types of phosphatidylcholines and two types of triglycerides. Levels of certain subclasses of phosphatidylcholine lipids and cholesterol esters could distinguish between CF and controls. Patients were divided into subgroups depending on the presence or absence of specific Participants were instructed not to eat or drink anything except water for at least two hours before saliva sample collection, which was carried out in the morning hours.