The US singer-songwriter's intimate second solo album is a mixed bag of featherlight vocals and strong collaborations.
Bennett’s voice is ultimately too thin to carry the emotive heft of her heartbreak material, and Broken Hearts Club works best when she facilitates others to take up its mantle. Its finest moments come when she collaborates. On her second album, Broken Hearts Club, this introspection continues, with varying results.
Editorial: Ministers have failed to deliver on parity of esteem for mental health services. Children are being badly let down.
But as long as the government rejects policies that would lift millions of families out of poverty, it is hard to see the outlook for the most vulnerable young people improving. The narrative of Covid’s impact on children is unfinished, and in parts contradictory. And there are multiple other factors, with rising concerns around the impact of social media use, particularly on teenage girls with their susceptibility to eating disorders, predating the pandemic. Already, government statistics show a 25% increase in the number of young people with a mental health need – from 61,830 in 2019 to 77,390 last year. Children’s mental health services in England are overstretched to the point where young people in some areas are waiting up to two years for treatment. “It is so appalling in our area it may as well not exist” was one GP’s description of a Yorkshire Camhs. Mental illness should be treated in people of all ages.
Paying monthly for the latest iPhone could bring convenience to users, and value to Apple's investors.
Apple’s potential move to subscription hardware could put telcos in a tough spot. And third, Apple will no doubt initially target its biggest fans and premium handset buyers; people who buy the most expensive iPhone and upgrade frequently. If subscribers get a new iPhone every 12 months, Apple could set the monthly cost significantly lower than the retail price divided by 12, because it would be getting the year-old devices back to refurbish and resell. Subscriptions are nothing new for entertainment, and they’re taking hold as a primary way to access software services as well. The service could also potentially give Apple more direct access to its most dedicated users, gaining instant test cases and evangelists for new hardware innovations. First, depending on how Apple’s subscription was priced, the status quo of second-hand iPhones holding their value could be disrupted.
CAR T-therapy has had lackluster success against solid tumors. Boosting it with an mRNA vaccine appears to make it more effective.
Using an mRNA vaccine to augment a patient’s CAR T-cell population is an idea that might well carry into future work in cell therapy, Kristin Anderson, a cell therapy researcher at the Fred Hutchinson Cancer Research Institute who did not work on the trial, told STAT. “Part of the problem with cell therapy in solid tumors is you do all this work to engineer T cells and then they might not get in and infiltrate tumors. Here, a CAR T-cell product targeting claudin-6 is novel and demonstrated promising results in selected solid tumors — though the impact on outcomes remains unclear.” “CAR T-cell therapy has become the standard of care for selected patients with [blood cancers,]” Fung said in a statement emailed to STAT. “Prior studies for solid tumors were disappointing. The idea is that immune cells known as antigen-presenting cells will take up the vaccine, produce claudin-6, and then present the protein to the CAR T-cells circulating in the body. “I was quite skeptical at first because CAR T-therapy hadn’t worked before in solid tumors, so we were very excited to see how the metastases disappeared and the patients improved,” Haanen said. That enables the CAR T-cell to see and attack these cancer cells.
Annual vaccination is the most important measure to prevent influenza and its complications. The influenza vaccine is recommended for all individuals aged 6 ...
The best way to protect yourself against getting both infections this winter is to make sure you’ve had your influenza vaccine and are fully vaccinated against COVID-19, including any recommended booster doses. Free influenza vaccines under the National Immunisation Program became available in April 2022. Vaccination experts recommend influenza vaccination for all people aged 6 months and over.
archTIS continues to see more and more opportunities around a data-centric approach to security. archTIS' experience and attribute-based...
The Strategy outlines initiatives that the Department is implementing in order to improve its data maturity and enhance the information available to the Australian Defence Force. KPMG will lead a consortium that includes several industry-leading suppliers such as Oracle and Microsoft, as well as three Australian Small to Medium Enterprises – archTIS, EPICON and SISU Solutions. archTIS’ experience and attribute-based access control methodology will continue to play a key role in forming strategic advantages with information for the warfighter and the Defence organisation that supports them.”
The campaign features five individual experts – a sushi chef, an expert fisherman, a property advisor, a wine expert and former AFL coach Kevin Sheedy – who ...
We hope our cheeky campaign will resonate with men across Australia and help him understand the comfort that awaits”. “The innovative pocket pouch in Bonds Total Package™ separates and supports, but obviously it’s a bit hard to show that on camera. With the majority of guys simply disengaged with their undies, we needed to find a new way to cut-through,” said Nathan Rogers, strategy director at Special.
Excited Young man wearing VR glasses. Image Credit: Francesco Carta fotografo/Getty. GamesBeat Summit 2022 returns with its largest event for leaders in gaming ...
However, in order for the metaverse to become truly beneficial for users in private and professional realms, there is a need for significant hardware improvements for realistic visual experiences. And, with over half of the world’s population, or more than 4.5 billion people, estimated to have access to the internet, it’s a lofty but plausible goal. To satisfy the viewer, an ultimate experience will be hardware that offers comfort through social ability, visual perception and wearability, as well as immersion through resolution, gestures and haptic interactions. This requires a well-established understanding of engineering, design, and manufacturing to provide complex optical and cost-effective solutions in high volume. Just shy of the start of 2022, a three-story yacht that exists only in the metaverse was also bought for $650,000, complete with a DJ booth, hot tubs and two helipads. It’s critical to collaborate with a trusted manufacturing partner that has established global experts in optical systems and technologies in the development of these innovations. Legacy devices lack the ability to provide impactful connections between digital and physical worlds that are seamless and interchangeable. It’s evident that the metaverse will heavily impact the economy and our lifestyles as its adoption becomes more prevalent. It’s important to note that the metaverse can only be realized through the technology that enables it. The concept of living in a world that is digitally created has been portrayed in countless Hollywood films depicting people who want to escape reality and dive into an alternate universe. With AR technology, users are operating a device that is essentially a lightweight, handheld or hands-free, immersive, and wearable computer. Still, many are left with questions about what the metaverse exactly is and how it would or could impact everyday lives.
A UN-led development plan for Ukraine launched on Monday, to provide immediate economic help and longer-term assistance to the millions left struggling to ...
In its latest economic update, The World Bank forecast that the region’s economy was set to shrink by 4.1 per cent this year, compared with a pre-war forecast of three per cent growth. The agency’s initiative also seeks to meet immediate humanitarian needs by leveraging Ukraine’s “human capital, economic capacities and natural resources”, and strengthen civil society to help uphold human rights for people’s “inclusion, protection and empowerment” in the recovery, UNDP said in a statement. “The war in Ukraine continues to inflict immense human suffering…with nine out of 10 people at risk of falling into poverty,” said Achim Steiner, UNDP Administrator. “As part of a coordinated UN response, UNDP has an unwavering commitment to stay and deliver for the people of Ukraine.”
Researchers have engineered a strain of bacteria that can help protect the natural flora of the human digestive tract from antibiotics and curb the ...
Furthermore, none of the mice that received the engineered bacteria developed opportunistic C. difficile infections, while all of the mice who received only antibiotics showed high levels of C. difficile in the gut. In contrast, they did find many genes for antibiotic resistance in the microbes that survived in mice who received antibiotics but not the engineered bacteria. "If the antibiotic action is not needed in the gut, then you need to protect the microbiota. This is similar to when you get an X-ray, you wear a lead apron to protect the rest of your body from the ionizing radiation," Cubillos-Ruiz says. Indiscriminate use of antibiotics on gut microbes can also contribute to the spread of resistance to the drugs. They engineered a strain of bacteria called Lactococcus lactis, which is normally used in cheese production, to deliver an enzyme that breaks down beta-lactam antibiotics. The engineered bacteria made their way to the intestine and began releasing beta-lactamase. They broke up the gene for beta-lactamase into two pieces, each of which encodes a fragment of the enzyme. One major complication that can occur is infection of C. difficile, a microbe that commonly lives in the gut but doesn't usually cause harm. "They cannot accomplish the same functions as the native microbes that you have nurtured throughout your life." In an effort to reduce those risks, MIT engineers have developed a new way to help protect the natural flora of the human digestive tract. Antibiotics are life-saving drugs, but they can also harm the beneficial microbes that live in the human gut.